How about non-Asians who experience flushing after drinking? This leaves more and more acetaldehyde in the blood upon continued consumption of alcohol. A lot of the information about the efficacy of Pepcid AC in stopping alcohol flushing is anecdotal. The major side effect when using antihistamines like Pepcid AC for alcohol flushing is that you can get drunk a lot quicker. Lee , Romance Comment. For example, drinking a beer will have a slower impact on your body than taking a shot.
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Search Search the site A person with one of each allele, a heterozygote, is exposed to less than half of normal ALDH2 activity. Skip to content. This leaves more and more acetaldehyde in the blood upon continued consumption of alcohol. As mentioned, famotidine targets ADH to slow the conversion of alcohol into acetaldehyde, which may indeed help your friends reduce flushing. Before the administration of alcohol, one-half of the subjects were given 50 mg of diphenhydramine H1 receptor antagonist and mg of cimetidine H2 receptor antagonist. Subscribe to our daily newsletter.